Terpene Awareness: Alpha-Pinene

Terpenes, an important part of cannabis.

 

Alpha-Pinene , sometimes referred to just as pinene or written α-pinene, is the most abundant terpene in nature. And it’s benefits are many.

Research suggests that alpha-Pinene may have skin and oral health supporting benefits and may support the proper function of the immune and respiratory systems. Oils rich in alpha-Pinene are great for supporting skin health. Helping to keep the skin looking healthy and may help to reduce the appearance of blemishes when applied topically.

 

 

 

Like its sibling, beta-pinene, alpha-pinene is most famous for its anti-inflammatory benefits.

These are helpful for diseases like arthritis, Crohn’s, and multiple sclerosis.

Alpha-Pinene working togheter with other cannabinoids:

  • Working in synergy with THC, alpha-pinene acts as a bronchodilator, opening up airways at low exposure levels to help conditions like asthma.
  • Working with CBD and CBN, it has a broad spectrum of antibiotic properties, which work against diseases like MRSA.
  • Alpha-pinene can also counteract unwanted effects of THC, such as anxiety and short-term memory. It works by inhibiting acetylcholinesterase activity in the brain, which helps you retain memories more efficiently.
  • Other benefits include euphoria, increased alertness, reduced oil production in oily skin, and most excitingly, anti-cancer properties. Studies suggest alpha-pinene can stop tumor growth and supplement chemotherapy treatments.

 

 

Here are some studies and info for you to read regarding alpha-Pinene:

 

(more…)

Keep track on us by following our social media!

Do you follow our social media?

Here are our Facebook & Instagram accounts!

On Facebook we share a lot of news and science regarding cannabis. Knowledge is power and it’s good to have the facts straight when debating cannabis.

 

 

This is our Instagram profile. Here you will see pictures of our CBD Crew strains, both from us and private growers.

Also CBD Crew at trade shows, memories & some knowledge.

Remember to tag us if you post about us, so we can see it #cbdcrew

This error message is only visible to WordPress admins

Error: The account for cbdcrew_official needs to be reconnected.
Due to recent Instagram platform changes this Instagram account needs to be reconnected in order to continue updating. Reconnect on plugin Settings page

Error: No posts found.

Make sure this account has posts available on instagram.com.

 

 

 

Secret Garden Inspirations, using CBD Crew genetics.

It’s so amazing to know our genetics are helping many of people out there in the world.

Getting feedback from private clients and wellness centers is something we treasure greatly.

Secret Garden Inspirations is using top resources and top quality genetics and it warms our hearts hearing from them and that they are doing great with our genetics.

Here is their page:

Secret Garden Inspirations

Thank you Secret Garden Inspirations for helping others.

ShifaShop

Is cannabis the new choice for seniors?


TheGuardian



In the Guardian today the story was: The mature stoner: why are so many seniors smoking weed?


This has been a tendency during the last years as cannabis has become more available and also the knowledge about cannabis more available. Some places it has even been legalized.


So may seniors have been on a cocktail of medication from their doctors, felling both the effects and the side effects. With all the knowledge being spread now about the things cannabis can help with, it would only be a matter of time beofre it reached the seniors as well.

Things like glaucoma, arthritis & joint pain, Parkinson, Alzheimer’s etc, are some conditions that cannabis can offer a significant relief from.





“The seniors using cannabis today aren’t your parents’ grandparents. The generation that camped out at Woodstock is now in its seventies. They’ve been around grass long enough to realize it’s not going to kill them, and are more open to the possibility it will come with health benefits. “

-TheGuardian





It’s true, the new group of seniors are not as their parents. Many have a different more reflective view on cannabis. And even tho they did not necessarily use it 10 years ago, it was often the, but where should I get it? Who should I do it with? What if somebody finds out? that stopped them.

Not that they were against cannabis in the first place. So many can now get cannabis without having to know ” a criminal” and people are much more open about it, do to more social acceptance.

With all the health benefits that we we know now, added to the availability, of course people will want to try cannabis for what ever reason they may have.

“While some doctors have expressed concerns about seniors self-medicating with weed, virtually everyone agrees the public health consequences of opioids are far worse. “


TheGuardian






Their methods of use is as broad as the average smokers. From smoking a good old joint to using specific products , like CBD oils for their joint pain. Stylish vape pens and delicious edibles. The more available cannabis gets, the more options people have to choose both what they want to taste, from a uplifting CBD Mango Haze to a calming CBD Nordle, or maybe a old school Afghan Haze for the picky one.

Some use it just for the medical benefits, and some even for it’s recreational effect. The knowledge available now makes it a lot easier to get advise on what is best for you.




We hope as more places around the wold open up for legalizing more people will have the ability to grow as well. We all know gardening is good for the health and it’s a passion many seniors have already. We believe they would be great growers. What a great way to get a lot of cost effective cannabis to use for the whole year, as we also know many senior are not living in luxury.

And in the end, is that not what we all want,

to be able to grow our own cannabis if we choose to?


 ShifaShop

CBD Crew seeds & full flower CBD dominant cannabinoid oils with added terpenes.

2019 a new year with new possibilities!

A new year has come, a new year for new possibilities and new battles.

We hope this year will bring down more unjust laws regarding cannabis and that people all around the world can soon be able to safely get cannabis products, not just CBD products, and be able to grow their own plants if they want to. Growing plants should not be illegal.

We hope that more people get to know about this amazing plant and what in can do for your health,

both your body and your mind.

We hope that with more legalization more knowledge will reach the people,

so they can make their own decisions based on real information.

We hope that more doctors will dare to learn about the endocannabinoid system

and gather knowledge to share with their patients.

We wish 2019 will be a great year for cannabis!

And yes, we will release new strains!

Remember to follow us on Facebook and Instagram as well!

[enjoyinstagram_mb]

CBD Therapy is back in stock!

CBD Therapy is on it’s way out to all shops again!

This low THC high CBD strain has helped many people all around the world since we released it. CBD Theapy is mostly under 1% THC and CBD up to 15%. This makes it a very potent CBD strain that is perfect for aiding with many diseases that benefits from CBD extracts.

CBD Therapy is a great strain to make high quality CBD full spectrum flower extracts also containing smaller amounts of all other cannabinoids and a broad selection of terpenes as well for terpene extraction. To to get the entourage effect in your product.

CBD Therapy is used for controlling epilepsy, spasms, reducing inflammation, helping with side effects of chemo, relieve anxiety and much more.  And also a great recreational to just to relax and reduce stress in daily life for those not looking to get to high.

 

 

You will soon find CBD Therapy seeds in most online seedshops and many growshops!

 

For wholesale, contact us at [email protected]

 

 

Children with epilepsy, who are we to deny them efficient aid?

 

Over the last years numerous people have come forth showing the incredible effects CBD have had on their children that suffer from various forms of epilepsy. Many have had to break the law or move far away from family and friends to places where they can legally obtain quality CBD products.  Many also try CBD products of lesser quality and don’t get the best results right away , due to the illegality and the mountains of industrial hemp products out there that vary very in quality.  So as a costumer you really have to know what questions to ask and what paperwork to expect to be shown from the supplier.

Here is a letter from Parents4Pot that they published years ago to try guide parents the right way:

 

 

EPILEPSY CBD

As respected members of the cannabis community, the undersigned groups and activists support full spectrum cannabis legislation and treatment for children with autism and seizure disorders. We agree that experience and research show proper and effective treatment requires the combination only the full cannabis plant can provide. We also agree that we need to support other organizations and activists who stand with us and concur that medical cannabis, by definition, includes the entire plant and all its chemical compounds.
As more parents learn that cannabis can help their children with autism and seizure disorders, it has become necessary to point out that the upshot of CBD only legislation and companies that produce CBD only products are giving what may be false hope to families who have exhausted other avenues of treatment.
We believe it is vital to understand the importance of using the entire cannabis plant as part of their solution. Parents who are worried that their children are “getting high” need to know that cannabis does not have the same psychoactive effect on the brain of a child with severe epilepsy or autism as it does on the average person. It actually works to slow the neurons that are firing so rapidly down, creating a healthier brain not a “high” brain. It is equally important for parents to know that they can give their children full plant cannabis without getting them “high.” Ingesting whole plant cold extract cannabis delivers non- psychoactive, non-psychotropic effects. This is an essential factor in building up the system that enables THC and CBD to work. It also allows the incorporation of the myriad beneficial components that cannabis provides.
The truth is that many parents who have tried CBD only treatments for their children with autism and epilepsy report no success or reduction in symptoms. They are forced to go to the black market to get the medicine they need. In fact, parents who are using straight THC as a rescue medication for their children’s seizures are seeing great results. Their children are cognitive and coherent instead of high and out of commission for a whole day.
Industrial hemp does not contain the amount of THC or CBD needed to make an effective treatment for epilepsy or autism. Also important to remember is that these CBD producers are unregulated; there is no proof that they are really providing what they promise. That, along with the lack of results are two good reasons to consider other options.
Parents, please feel free to contact the groups listed below to learn more about the differences between full plant and CBD only cannabis treatments to make a more informed decision. Your child’s life depends on it.

 

Websites:
www.parents4pot.org

We believe people should be able to grow their own plants and make their own CBD rich products at home safely. Which is one of the reasons we have developed all our CBD rich strains.  For those looking for low THC, high CBD, we recommend our CBD Therapy

Growing yourself is the most cost effective way of getting CBD products as buying a lot of tinctures can be expensive for low income households and you will always be sure what you actually have. And hopefully soon people will also be able to get high quality CBD product made form low THC, high CBD cannabis flowers over the counter at their local CBD shops, health food stores or even pharmacies.

 

 

For more info and studies regarding cannabinoids and epilepsy,  visit:

 

ProjcetCBD

 

CBD-rich cannabis extract as compared to single-molecule CBD

 

 

CB1 & CB2 + GPR55? Another receptor for cannabinoids?

Story from: CannabisNow

 

Is there a Third Cannabinoid Receptor?

 

We have long known about the two cannabinoid receptors: CB1 and CB2.  Now there is growing awareness of a third such receptor that was identified in 2007.

This receptor, GPR55, may be key to understanding a wide spectrum of therapeutic applications for cannabinoids — and especially CBD.

The GPR55 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.

 

 

A scientific study published last year was the latest to focus the research community on the potential of the GPR55 receptor, which is now known to be the third identified receptor in the human endocannabinoid system. The study found a role for the receptor in the use of CBD to treat Dravet syndrome, a rare and severe form of epilepsy.The research team from the University of Washington at Seattle noted that they saw potential to “extend the scope of CBD treatment to autistic-like behaviors, and provide initial mechanistic insights into CBD’s therapeutic actions,” according to the abstract in the Proceedings of the National Academy of Sciences (PNAS).In the human endocannabinoid system, cannabinoid receptors are the specialized protein molecules that interact with the active cannabis compounds in the human body. Since the 1990s, scientists have known about the receptors CB1 and CB2, but research is continuing to emerge about the GPR55 receptor and the role it appears to play in the endocannabinoid system as another unique cannabinoid receptor. 

The Recent History of GPR55 Receptor Research

It was a 2007 study published by the National Center for Biotechnology Information (NCBI) that first identified what was until then known as the “orphan receptor” GPR55  — meaning its function had not yet been determined — as a “novel cannabinoid receptor.” In the years since then, evidence has been mounting that the GPR55 receptor could explain the actual biological mechanisms for many of the benefits reported by cannabis users.

A 2009 study published by PNAS found a role for the GPR55 receptor in regulating osteoclast function — that is to say, bone formation and healing. A 2016 study published by the NCBI found a similar role in controlling inflammation.

Most impressive was a 2015 overview published by Frontiers in Pharmacology, which found that two orphan receptors as well as the “deorphanized” GPR55 “may be promising therapeutic targets, with diverse physiological roles,” ranging from gastrointestinal to bone disorders.

The Science Behind the GPR55 Receptor

The GPR55 receptor — the 55th in the series of G-protein-coupled receptors that also include CB1 and CB2 — is found in the brain and gastrointestinal tract. The G stands for guanine, which is a nucleotide base, meaning it is one of the so-called “building blocks” of DNA. Guanine is associated with the G proteins because of how these receptors interact with cells. The receptor “receives the chemical and sends messages to cells such as neurons,” according to Robert Sindelar, chief science officer and head of product development at BAS Research — a Berkeley, California-based licensed manufacturer of “white-label” cannabis products.

“The endocannabinoid system has been a black box for many years, partially due to federal restrictions on research,” Sindelar told Cannabis Now. “Basically, we’re starting to find out: How does this stuff do this? People with seizures are being affected by CBD. How does this actually happen? With the new work on GPR55, scientific research is catching up with what traditional knowledge and anecdotal evidence have documented for hundreds of years.”

As an example, Sindelar points to Dravet syndrome: “It’s a rare disease that was basically thought to be untreatable. Many sufferers have found their only relief in taking a steady regimen of CBD. Now they’ve found the mechanism or mode of action by which CBD sends a message to something in the brain that tells a child suffering from Dravet syndrome to either have a seizure or not.”

Because there is a growing body of evidence around the GPR55 receptor, including the 2017 study which discovered the GPR55 receptor’s role in treating Dravet syndrome, Sindelar says there is more pressure on the academic community to continue researching the GPR55 receptor as a potential target for epilepsy treatment, especially in terms of how it interacts with CBD.

And Sindelar sees these studies as ultimately having political ripples. “Research is eliminating the scientific mystery about what people see in practice, or anecdotally,” he said. “This could provide the body of evidence we need to deschedule these chemicals. In many ways, I feel it’s inevitably leading to a change in the way cannabinoids are federally classified to allow further investigation into these things. That opens [research] up to federal funding.”

 

 

 

Study on GPR55
Published online 2013 Jul 1.

Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management

 

Conclusion:

 

“Because of its cannabinoid sensitivity and similar tissue localization, GPR55 can explain some of the effects observed that are not mediated by the canonical cannabinoid receptors Cb1 and Cb2. To date, LPI has been described as the endogenous GPR55 ligand, but endocannabinoids AEA, 2-AG, and the agonist O-1602 can also activate it. Therefore, GPR55 is likely the first LPI:  receptor described. …….

……Additional studies to elucidate the role of endocannabinoid GPR55 ligands in GPR55 physiology and pathophysiology are also warranted, as endocannabinoids have been shown to play a role in inflammation, cancer, liver disease, and inflammatory disorders of the intestinal tract, to name a few. In conclusion, GPR55 has emerged as a promising candidate for the development of novel anticancer therapeutic strategies.”

 

 

 

Cannabis, a ‘Relatively Safe Drug’ UN declares

 

For the first time ever, the World Health Organization met last week to review the safety of cannabis.

What will this mean for the fight for legalization worldwide? Well it’s to soon to say, but at least we hope that this is a step in the right direction. We at CBD Crew have always said the fight is not over before people all around the world can safely grow their own plants and also have access to dispensaries if they are in a situation where they can not grow their own. Lets see what happens now and keep sharing knowledge so this will happen sooner than later!

 

 

Story from Herb:

 

The United Nations’ drug committee found that marijuana is a “relatively safe drug,” noting that millions of people worldwide are already using it to manage a multitude of medical conditions.

The findings could impact a recommendation the agency is preparing to the UN on the “need for and level of international control” over cannabis. Marijuana prohibition is in force almost worldwide under international drug treaties originally dating back to 1961.

Worldwide, an estimated 183 million adults used cannabis in 2015, according to the report. Weed is cultivated in 135 countries and is the “most widely illicitly produced drug worldwide.”

The UN agency conducted a survey of 953 medical marijuana patients from 31 nations. Most of them said they’d used cannabis-based medicines for years. Most were also under the supervision of a physician. But a majority said they’d also tried cannabis before getting a doctor’s recommendation.

 

Used most often for pain

 

Cannabis, in various forms, is used most often to control back pain, sleep disorders, anxiety, depression, post-injury pain, and multiple sclerosis, according to the report. Pain, sleep disturbances, and anxiety were the three conditions most commonly treated with cannabis.

An estimated 2.2 million patients use cannabis medicinally in the United States. Pain is the most often cited qualifying condition. Pain also ranked high among cannabis patients in Israel and Canada. Meanwhile, 30 percent of cannabis patients in the United Kingdom reported using the herb to treat multiple sclerosis. (Cannabis-infused Sativex spray is commonly prescribed for M.S. in Great Britain.)

The committee, interestingly, pointed to a “wealth of preclinical literature” indicating cannabinoids “reduce cancer cell proliferation” and inhibit “cancer cell migration and angiogenesis in numerous cancer cell types.” This seems to be an area of great promise, with more research to come.

Then there are the recreational cannabis users. An estimated 3 to 5 percent of people globally have tried marijuana for non-medical reasons, according to the UN report. Interestingly, two studies examined by the report found no significant differences between those who use cannabis medically and nonmedical users.

One study, however, found medical patients used more cannabis daily than recreational consumers. Medical patients were more likely to be in poorer health than recreational users. But the study found they also had lower levels of both alcoholism and nonprescription drug use.

A nurse lights a cannabis cigarette for a patient at the Hadarim nursing home on March 09, 2011 in Kibutz Naan, Israel. In conjunction with Israel’s Health Ministry, The Tikun Olam company is currently distributing cannabis for medicinal purposes to over 1800 people in Israel. (Photo by Uriel Sinai/Getty Images)

Research lagging

 

The UN report noted that scientific research into cannabis is inadequate. There’s plenty of public interest, but very few clinical trials have been done, due largely to the legal strictures of prohibition.

“Barriers to research in the USA include the difficulty of navigating through several federal agencies (including the aforementioned DEA, FDA) as well as research ethics boards and local and state oversight concerns,” according to the report.

The UN report, interestingly enough, also noted problems in quality control from the current single source of cannabis for scientific research in the US. All federal cannabis is grown at one farm on the campus of The University of Mississippi in Oxford, Miss.

“The current international policies on cannabis use are outdated and are having a detrimental impact on patients in the US and worldwide,” said Steph Sherer, executive director of Americans for Safe Access (ASA). “These policies do not reflect the reality of over 30 countries globally that have passed medical cannabis laws.”

 

 

UN Chief Wants to Decrim All Drugs

 

UN Secretary-General António Guterres in March gave a speech supporting the decriminalization of all drugs. His comments went counter to the UN’s top narcotics officials. They’d released a report earlier the same week criticizing cannabis legalization around the world.

“Current efforts have fallen short of the goal to eliminate the illicit drugs market,” said Guterres in a video message. “We can promote efforts to stop organized crime while protecting human rights, enabling development and ensuring rights-based treatment and support. I am particularly proud of the results of the reforms I introduced in Portugal when I was prime minister almost 20 years ago.”

Guterres, as prime minister of Portugal, introduced the decriminalization of all drugs in that nation in 2001. The policy is viewed as a success and has been praised by advocates around the world. Overdose deaths, HIV infections, and even overall use has reduced under decrim in the country.